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Tiamulin Fumarate

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Tiamulin Fumarate, Tiamulin Hydrogen Fumarate

CAS number: 55297-96-6

Molecular formula: C28H47NO4S.C4H4O4

molecular weight:609.82

Shelf Life: 5years

Packing: 25kg/drum

Specification:

Items

Specification

Result

Description

White or almost white crystalline powder

Complies

Identification

HPLC: The retention time of tiamulin fumarate peak obtained from the test solution corresponds to that obtained from the standard solution.

Infra-red spectrum: Infra-red spectrum of the sample corresponds to that of the reference standard.

Complies

Color and clarity of

solution

The solution should be clear and colorless,

and the absorbance at 400nm and 650nm

is not greater than 0.150 and 0.030

Clear and colorless

400nm 0.030

650nm 0.011

Loss on drying

Not more than 0.5%

0.1%

Melting temperature

143-149oC

147oC

Specific Rotation

+24~+28o

+28oC

PH

3.1-4.1

3.6

Content of fumarate

83.7mg-87.3mg

85.2mg

Residue on ignition

Not more than 0.1%

0.03%

Heavy metals

Not more than 0.001%

Complies

Residual solvent

Total: £3000 ppm

1098ppm

Methanol: £3000 ppm

555ppm

MIBK: £2250 ppm

543ppm

Chromatographic

purity

Any identified impurity:£1.0%

Complies

Any unidentified impurity :£0.5%

Complies

Total impurities:£2.0%

1.38%

Assay (Calculated

on the dried basis)

98.0-102.0%

98.7%

Conclusion

The product meets the specifications of USP38

 

 

 

Function Tiamulin is mainly used to prevent and cure chicken chronic respiratory disease, Mycoplasma pneumoniae (asthma), actinomycosis and Treponema. Low dose can promote growth and improve feed utilization.

 

Application Don't use together with polyether ionophores such as Monesin,Salinomycin etc.
Don't touch with eyes and skin.

 

 


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