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Tadalafil
CAS number： 171596-29-5
Molecular formula：C22H19N3O4
Molecular weight： 389.40
Packing: 1kg/bag or 25kg/drum
Valid time: 2 years
Specification:
Items | Specification | Results |
Appearance | White or almost white crystalline powder | White crystalline powder |
Solubility | Practically insoluble in water, freely soluble in dimethyl sulfoxide, slightly soluble in methylene chloride | Conformed |
Melting point | 302℃~303℃ | 303℃ |
Identification | The infrared absorption spectrum is concordant with the reference spectrum | Conformed |
The principal peak in the chromatogram obtained with the test solution is similar in retention time and size to the principal peak in the chromatogram obtained with reference solution | Conformed | |
Rotation | + 78.0°to + 84.0° | +80.6° |
Impurities A, B and C | Impurity A, B and C≤0.1% | Non-detected |
Loss on drying | ≤0.5% | 0.23% |
Residue on ignition | ≤0.1% | 0.04% |
Heavy metals | ≤10ppm | Conformed |
Related substances（HPLC）
| individual impurity≤0.1% | 0.09% |
Total unknown impurity≤1.0% | 0.18% | |
Residual Solvents
| Methanol≤0.3% | Non-detected |
IPA≤0.5% | Non-detected | |
Methyl Acetate≤0.5% | Non-detected | |
EA≤0.5% | Non-detected | |
DCM≤0.06% | Non-detected | |
AceticAcid≤0.5% | Non-detected | |
Assay | ≥99.0% | 99.7% |
Conclusion | The test results conform with EP 9 Specification. | |
Function:
Tadalafil is an oral drug for the treatment of ED, used in the treatment of erectile dysfunction and premature ejaculation, erectile function impairment and premature ejaculation has very significant improvements.
There are over 1500 documents to prove the caused by different causes impotence premature ejaculation, knew the success rate is above 80%, and show its reliable curative effect, through the use of more than 20 million people worldwide, proved its long-term stability.
The safety of 25 to 60 minutes of work function to coincide with a time needed for foreplay, knew the time adjustment in the highest drug concentration time, help both husband and wife a satisfactory sex life.
Application:
1. Tadalafil usually takes 30 to 60 minutes for tadalafil to work for erectile dysfunction. You can take tadalafil once a day, at least 30 minutes before you want to have sex.
2. Taking tadalafil on its own is not enough to cause an erection. You need to be sexually aroused for it to work.
3. Many men do not have any side effects from tadalafil, while some have mild side effects. These may include headaches, back pain, muscle aches, pain in your arms and legs, facial flushes, stuffy nose, and indigestion.
4. Do not take tadalafil if you also take medicines called nitrates (often prescribed for chest pain). This combination can cause dangerously low blood pressure.
5. Tadalafil is sometimes called the brand names Cialis (for erectile dysfunction and benign prostatic enlargement) or Adcirca (for pulmonary hypertension).
Tadalafil
CAS number： 171596-29-5
Molecular formula：C22H19N3O4
Molecular weight： 389.40
Packing: 1kg/bag or 25kg/drum
Valid time: 2 years
Specification:
Items | Specification | Results |
Appearance | White or almost white crystalline powder | White crystalline powder |
Solubility | Practically insoluble in water, freely soluble in dimethyl sulfoxide, slightly soluble in methylene chloride | Conformed |
Melting point | 302℃~303℃ | 303℃ |
Identification | The infrared absorption spectrum is concordant with the reference spectrum | Conformed |
The principal peak in the chromatogram obtained with the test solution is similar in retention time and size to the principal peak in the chromatogram obtained with reference solution | Conformed | |
Rotation | + 78.0°to + 84.0° | +80.6° |
Impurities A, B and C | Impurity A, B and C≤0.1% | Non-detected |
Loss on drying | ≤0.5% | 0.23% |
Residue on ignition | ≤0.1% | 0.04% |
Heavy metals | ≤10ppm | Conformed |
Related substances（HPLC）
| individual impurity≤0.1% | 0.09% |
Total unknown impurity≤1.0% | 0.18% | |
Residual Solvents
| Methanol≤0.3% | Non-detected |
IPA≤0.5% | Non-detected | |
Methyl Acetate≤0.5% | Non-detected | |
EA≤0.5% | Non-detected | |
DCM≤0.06% | Non-detected | |
AceticAcid≤0.5% | Non-detected | |
Assay | ≥99.0% | 99.7% |
Conclusion | The test results conform with EP 9 Specification. | |
Function:
Tadalafil is an oral drug for the treatment of ED, used in the treatment of erectile dysfunction and premature ejaculation, erectile function impairment and premature ejaculation has very significant improvements.
There are over 1500 documents to prove the caused by different causes impotence premature ejaculation, knew the success rate is above 80%, and show its reliable curative effect, through the use of more than 20 million people worldwide, proved its long-term stability.
The safety of 25 to 60 minutes of work function to coincide with a time needed for foreplay, knew the time adjustment in the highest drug concentration time, help both husband and wife a satisfactory sex life.
Application:
1. Tadalafil usually takes 30 to 60 minutes for tadalafil to work for erectile dysfunction. You can take tadalafil once a day, at least 30 minutes before you want to have sex.
2. Taking tadalafil on its own is not enough to cause an erection. You need to be sexually aroused for it to work.
3. Many men do not have any side effects from tadalafil, while some have mild side effects. These may include headaches, back pain, muscle aches, pain in your arms and legs, facial flushes, stuffy nose, and indigestion.
4. Do not take tadalafil if you also take medicines called nitrates (often prescribed for chest pain). This combination can cause dangerously low blood pressure.
5. Tadalafil is sometimes called the brand names Cialis (for erectile dysfunction and benign prostatic enlargement) or Adcirca (for pulmonary hypertension).
