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Oxytetracycline Hydrochloride

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Oxytetracycline Hydrochloride

CAS number:2058-46-0

Molecular formula: C22H24N2O9.HCl

Molecular weight: 496.90

Shelf Life: 4 years

Packing: 25kg/drum

Quality: please kindly download in our website

Specification:

TESTS

SPECIFICATION

RESULTS

CHARACTERS

Appearance

Yellow, Crystalline powder, hygroscopic.

Complies

Solubility

Freely soluble in water, sparingly soluble in ethanol, solutions in water become turd on standing, owing to the precipitation of Oxytetracycline.

Complies

Identification

According to BP2013

Complies

TESTS

pH

2.3 ~2.9

2.3 to 2.9

2.5

Specific absorbance

270 to 290 (anhydrous substance)

271

Specific optical Rotation

-188°to -200° (anhydrous substance)

-190°

Heavy metals

Maximum 50ppm

<50ppm

Light absorbing Impurities

A(0.2%, 1cm, 430nm)<0.50

Absorbance at 430nm shall not more than 0.50

0.21

A(1%, 1cm, 490nm)<0.20

Absorbance at 490nm shall not more than 0.20

0.090

Related substances

Content of impurity peak meets the requirements

Complies

Sulfated ash

Maximum 0.5%

0.08%

Water

Maximum 2.0%

1.1%

Assay (HPLC)

95.0% to 102.0%. Anhydrous substance

96.0%

Conclusion: This Product Fullfils Bp2013

 

 

 

Function  

 It is a broad-spectrum antibiotic, its antibacterial spectrum and antibacterial principle is basically the same with tetracycline.

It mainly has antibacterial activity to Gram-positive bacteria, meningococcal, and gram-negative bacteria such as Micrococcus gonococcus.

It has a strong bactericidal effect to Gram-positive bacteria such as Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Salmonella, Serratia, Neisseria gonorrhoeae, etc

Applications

(1) rickettsial disease, including epidemic typhus, endemic typhus, rocky mountain hot, tropical

typhus and Q fever

(2) the mycoplasma infection

(3) the chlamydial infection, including psittacosis, knob, lymphatic meat tooth is swollen, nonspecific

urethritis, lose eggs bamboo inflammation, cervicitis and trachoma.

(4) relapsing fever.

(5) the undulant disease.

(6) cholera.

(7) from fever.

(8) the plague.

(9) soft chancre.

Treating undulant disease and plague with aminoglycoside joint application.

 


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