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Oxytetracycline Hydrochloride
CAS number：2058-46-0
Molecular formula： C22H24N2O9.HCl
Molecular weight： 496.90
Shelf Life: 4 years
Packing: 25kg/drum
Quality: please kindly download in our website
Specification:
TESTS | SPECIFICATION | RESULTS |
CHARACTERS | ||
Appearance | Yellow, Crystalline powder, hygroscopic. | Complies |
Solubility | Freely soluble in water, sparingly soluble in ethanol, solutions in water become turd on standing, owing to the precipitation of Oxytetracycline. | Complies |
Identification | According to BP2013 | Complies |
TESTS | ||
pH | 2.3 ～2.9 2.3 to 2.9 | 2.5 |
Specific absorbance | 270 to 290 (anhydrous substance) | 271 |
Specific optical Rotation | -190° | |
Heavy metals | Maximum 50ppm | ＜50ppm |
Light absorbing Impurities | A(0.2%, 1cm, 430nm)＜0.50 Absorbance at 430nm shall not more than 0.50 | 0.21 |
A(1%, 1cm, 490nm)＜0.20 Absorbance at 490nm shall not more than 0.20 | 0.090 | |
Related substances | Content of impurity peak meets the requirements | Complies |
Sulfated ash | Maximum 0.5% | 0.08% |
Water | Maximum 2.0% | 1.1% |
Assay (HPLC) | 95.0% to 102.0%. Anhydrous substance | 96.0% |
Conclusion: This Product Fullfils Bp2013 | ||
Function
It is a broad-spectrum antibiotic, its antibacterial spectrum and antibacterial principle is basically the same with tetracycline.
It mainly has antibacterial activity to Gram-positive bacteria, meningococcal, and gram-negative bacteria such as Micrococcus gonococcus.
It has a strong bactericidal effect to Gram-positive bacteria such as Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Salmonella, Serratia, Neisseria gonorrhoeae, etc
Applications
(1) rickettsial disease, including epidemic typhus, endemic typhus, rocky mountain hot, tropical
typhus and Q fever
(2) the mycoplasma infection
(3) the chlamydial infection, including psittacosis, knob, lymphatic meat tooth is swollen, nonspecific
urethritis, lose eggs bamboo inflammation, cervicitis and trachoma.
(4) relapsing fever.
(5) the undulant disease.
(6) cholera.
(7) from fever.
(8) the plague.
(9) soft chancre.
Treating undulant disease and plague with aminoglycoside joint application.
Oxytetracycline Hydrochloride
CAS number：2058-46-0
Molecular formula： C22H24N2O9.HCl
Molecular weight： 496.90
Shelf Life: 4 years
Packing: 25kg/drum
Quality: please kindly download in our website
Specification:
TESTS | SPECIFICATION | RESULTS |
CHARACTERS | ||
Appearance | Yellow, Crystalline powder, hygroscopic. | Complies |
Solubility | Freely soluble in water, sparingly soluble in ethanol, solutions in water become turd on standing, owing to the precipitation of Oxytetracycline. | Complies |
Identification | According to BP2013 | Complies |
TESTS | ||
pH | 2.3 ～2.9 2.3 to 2.9 | 2.5 |
Specific absorbance | 270 to 290 (anhydrous substance) | 271 |
Specific optical Rotation | -190° | |
Heavy metals | Maximum 50ppm | ＜50ppm |
Light absorbing Impurities | A(0.2%, 1cm, 430nm)＜0.50 Absorbance at 430nm shall not more than 0.50 | 0.21 |
A(1%, 1cm, 490nm)＜0.20 Absorbance at 490nm shall not more than 0.20 | 0.090 | |
Related substances | Content of impurity peak meets the requirements | Complies |
Sulfated ash | Maximum 0.5% | 0.08% |
Water | Maximum 2.0% | 1.1% |
Assay (HPLC) | 95.0% to 102.0%. Anhydrous substance | 96.0% |
Conclusion: This Product Fullfils Bp2013 | ||
Function
It is a broad-spectrum antibiotic, its antibacterial spectrum and antibacterial principle is basically the same with tetracycline.
It mainly has antibacterial activity to Gram-positive bacteria, meningococcal, and gram-negative bacteria such as Micrococcus gonococcus.
It has a strong bactericidal effect to Gram-positive bacteria such as Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Salmonella, Serratia, Neisseria gonorrhoeae, etc
Applications
(1) rickettsial disease, including epidemic typhus, endemic typhus, rocky mountain hot, tropical
typhus and Q fever
(2) the mycoplasma infection
(3) the chlamydial infection, including psittacosis, knob, lymphatic meat tooth is swollen, nonspecific
urethritis, lose eggs bamboo inflammation, cervicitis and trachoma.
(4) relapsing fever.
(5) the undulant disease.
(6) cholera.
(7) from fever.
(8) the plague.
(9) soft chancre.
Treating undulant disease and plague with aminoglycoside joint application.
