 |
| Quantity: | |
|---|---|
Norfloxacin Hydrochloride,Norfloxacin HCL, Norfloxacin
CAS number：104142-93-0 and 70458-96-7
Molecular formula： C16H19ClFN3O3 and C16H18FN3O3
molecular weight：355.79 and 319.33
Packing: 25kg/drum
Shelf Life: 3 years
Specification:
Tests |
Acceptance Criteria |
Results |
Characters | Almost white to light yellow crystalline powder | Conforms |
Identification | Conforms | Conforms |
Bulk density untapped |
0.45-0.70g/ml |
0.63g/ml |
Bulk density tapped |
0.70-0.85g/ml |
0.75g/ml |
Related substances |
≤0.5% | Conforms |
Loss on drying |
≤1.0% (105℃) |
0.03% |
Residue on ignition |
≤0.1% |
0.05% |
Heavy metals |
≤ 15ppm |
<15ppm |
Assay |
99.0-101.0% |
99.8% |
Function
The product is a fluoroquinolone antibacterials, with broad-spectrum antibacterial effect, especially for aerobic gram-negative bacilli high antibacterial activity, on the following in vitro bacterial with good antibacterial effect:Enterobacteriaceae most bacteria, including citric acid bacterium, Enterobacter cloacae, Enterobacter aerogenes,enterobacter, Escherichia coli rare bacterium, Cray Borrelia bacteria of the genus, proteus, Salmonella, Shigella,yersinia genus Vibrio, etc.. Norfloxacin lactate
Norfloxacin has in vitro antibacterial activity of multi-drug resistant. Penicillin-resistant Neisseria gonorrhoeae, Haemophilus influenzae and Moraxella catarrhalis is also a good antibacterial effect. Norfloxacin is Fungicide, by acting on bacterial DNA helicase of the A subunit, inhibit DNA synthesis and replication leading to bacterial death.
Application
Norfloxacin is used for prevention of spontaneous bacterial peritonitis in cirrhotic patients who have a low ascites fluid protein level, impaired renal function, severe liver disease, have had a prior episode of spontaneous bacterial peritonitis, or esophageal variceal bleeding.
Norfloxacin Hydrochloride,Norfloxacin HCL, Norfloxacin
CAS number：104142-93-0 and 70458-96-7
Molecular formula： C16H19ClFN3O3 and C16H18FN3O3
molecular weight：355.79 and 319.33
Packing: 25kg/drum
Shelf Life: 3 years
Specification:
Tests |
Acceptance Criteria |
Results |
Characters | Almost white to light yellow crystalline powder | Conforms |
Identification | Conforms | Conforms |
Bulk density untapped |
0.45-0.70g/ml |
0.63g/ml |
Bulk density tapped |
0.70-0.85g/ml |
0.75g/ml |
Related substances |
≤0.5% | Conforms |
Loss on drying |
≤1.0% (105℃) |
0.03% |
Residue on ignition |
≤0.1% |
0.05% |
Heavy metals |
≤ 15ppm |
<15ppm |
Assay |
99.0-101.0% |
99.8% |
Function
The product is a fluoroquinolone antibacterials, with broad-spectrum antibacterial effect, especially for aerobic gram-negative bacilli high antibacterial activity, on the following in vitro bacterial with good antibacterial effect:Enterobacteriaceae most bacteria, including citric acid bacterium, Enterobacter cloacae, Enterobacter aerogenes,enterobacter, Escherichia coli rare bacterium, Cray Borrelia bacteria of the genus, proteus, Salmonella, Shigella,yersinia genus Vibrio, etc.. Norfloxacin lactate
Norfloxacin has in vitro antibacterial activity of multi-drug resistant. Penicillin-resistant Neisseria gonorrhoeae, Haemophilus influenzae and Moraxella catarrhalis is also a good antibacterial effect. Norfloxacin is Fungicide, by acting on bacterial DNA helicase of the A subunit, inhibit DNA synthesis and replication leading to bacterial death.
Application
Norfloxacin is used for prevention of spontaneous bacterial peritonitis in cirrhotic patients who have a low ascites fluid protein level, impaired renal function, severe liver disease, have had a prior episode of spontaneous bacterial peritonitis, or esophageal variceal bleeding.
