Dexamethasone Sodium Phosphate
Molecular formula： C22H28FNa2O8P
Molecular weight： 516.40
Packing: 1kg/tin/carton; 2kg/tin/carton
Valid time: 3 years
White or almost white, very hygroscopic powder
Freely soluble in water, slightly soluble in ethanol (96 per cent), practically insoluble in methylene chloride.
Appearance of Solution
Not more intensely coloured than reference solution B7
The spectrum should be accord to the dexamethasone sodium phosphate CRS
The principal spot in the chromatogram obtained with test solution is similar in position and size to the principal spot in the chromatogram obtained with reference solution.
Specific Optical Rotation
Impurity A≤ 0.5%
Impurity B≤ 0.5%
Total impurities≤ 1.0%
Ethanol and Water
97.0 per cent to 103.0 per cent (anhydrous substance).
To be conform with BP2010
1.Dexamethasone sodium phosphate is a synthetic adrenocortical steroid used to treat inflammatory and autoimmune
2.Dexamethasone sodium phosphate is used to treat conditions such as skin conditions, ulcerative colitis, psoriasis,
arthritis, allergic disorders and breathing related problems;
3.Dexamethasone sodium phosphate is given to cancer patients undergoing chemotherapy, to prevent certain side-effects:
4.Dexamethasone sodium phosphate is also used in the treatment of high altitude cerebral edema.