 |
| Quantity: | |
|---|---|
产品详情文案：
Dexamethasone Sodium Phosphate
CAS number：55203-24-2
Molecular formula： C22H28FNa2O8P
Molecular weight： 516.40
Packing: 1kg/tin/carton; 2kg/tin/carton
Valid time: 3 years
Specification:
Test Items | Specifications | Results | |
Appearance | White or almost white, very hygroscopic powder | Conform | |
Solubility
| Freely soluble in water, slightly soluble in ethanol (96 per cent), practically insoluble in methylene chloride. | Conform | |
Appearance of Solution | Not more intensely coloured than reference solution B7 | Conform | |
Identification | |||
IR | The spectrum should be accord to the dexamethasone sodium phosphate CRS | Conform | |
TLC | The principal spot in the chromatogram obtained with test solution is similar in position and size to the principal spot in the chromatogram obtained with reference solution. | Conform | |
Identification | |||
pH | 7.5~9.5 | 8.7 | |
Specific Optical Rotation | +75°~ +83° | +77.5° | |
Related substances | Impurity A≤ 0.5% | not detected | |
Impurity B≤ 0.5% | 0.05% | ||
Total impurities≤ 1.0% | 0.79% | ||
Ethanol and Water | ≤ 13.0% | 8.6% | |
Content | 97.0 per cent to 103.0 per cent (anhydrous substance). | 99.6% | |
Conclusion | To be conform with BP2010 | ||
1.Dexamethasone sodium phosphate is a synthetic adrenocortical steroid used to treat inflammatory and autoimmune
conditions;
2.Dexamethasone sodium phosphate is used to treat conditions such as skin conditions, ulcerative colitis, psoriasis,
arthritis, allergic disorders and breathing related problems;
3.Dexamethasone sodium phosphate is given to cancer patients undergoing chemotherapy, to prevent certain side-effects:
4.Dexamethasone sodium phosphate is also used in the treatment of high altitude cerebral edema.
产品详情文案：
Dexamethasone Sodium Phosphate
CAS number：55203-24-2
Molecular formula： C22H28FNa2O8P
Molecular weight： 516.40
Packing: 1kg/tin/carton; 2kg/tin/carton
Valid time: 3 years
Specification:
Test Items | Specifications | Results | |
Appearance | White or almost white, very hygroscopic powder | Conform | |
Solubility
| Freely soluble in water, slightly soluble in ethanol (96 per cent), practically insoluble in methylene chloride. | Conform | |
Appearance of Solution | Not more intensely coloured than reference solution B7 | Conform | |
Identification | |||
IR | The spectrum should be accord to the dexamethasone sodium phosphate CRS | Conform | |
TLC | The principal spot in the chromatogram obtained with test solution is similar in position and size to the principal spot in the chromatogram obtained with reference solution. | Conform | |
Identification | |||
pH | 7.5~9.5 | 8.7 | |
Specific Optical Rotation | +75°~ +83° | +77.5° | |
Related substances | Impurity A≤ 0.5% | not detected | |
Impurity B≤ 0.5% | 0.05% | ||
Total impurities≤ 1.0% | 0.79% | ||
Ethanol and Water | ≤ 13.0% | 8.6% | |
Content | 97.0 per cent to 103.0 per cent (anhydrous substance). | 99.6% | |
Conclusion | To be conform with BP2010 | ||
1.Dexamethasone sodium phosphate is a synthetic adrenocortical steroid used to treat inflammatory and autoimmune
conditions;
2.Dexamethasone sodium phosphate is used to treat conditions such as skin conditions, ulcerative colitis, psoriasis,
arthritis, allergic disorders and breathing related problems;
3.Dexamethasone sodium phosphate is given to cancer patients undergoing chemotherapy, to prevent certain side-effects:
4.Dexamethasone sodium phosphate is also used in the treatment of high altitude cerebral edema.
