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Ceftiofur HCL

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Product Name

Ceftiofur Hydrochloride, Ceftiofur HCL


Items

Standard

Results

Appearance

White or off-white crystalline powder

Comply

Assay

98.0~103.0%

(% w/w by HPLC as C19H17N3O7S3.HCl on anhydrous basis)

99.68%

Solubility

Soluble in N,N-Dimethylacetamide, slightly soluble in

5% aqueous sodium bicarbonate solution and in methanol

Comply

Identification

IR:

IR spectrum of sample as KBr pellet is concordant with similar recorded spectrum of working standard

Comply

HPLC:

The retention time of the major peak in the chromatogram of the sample preparation corresponds to that in the chromatogram of the standard preparation as obtained in the assay

Comply

Related Substance

Single largest impurity

≤1.0%

0.48%

Total impurities

≤2.0%

1.26%

Moisture

≤4.0%

3.22%

PH

2.0~3.0

2.51

Absorbance

≤0.500A

0.345A

Specific rotation

-115°  ~  -125°

-122.52°

Residue on ignition

≤0.5%

0.05%

Particle size

90%<10um

Comply

Sterility

Comply

Comply

Storage

Keep tightly closed. If long time no use, Please keep below 5 °C.

Determination

Complies with enterprise standard

Function:

 

1. protects epithelial cell membranes in the stomach and restores them to their normal metabolism; 

2. acts as an antioxidant and protects the stomach from alcohol and smoking-induced damage; 
3 has anti-inflammatory properties and moderates production of interleukin-8; 
4. adheres to ulcerations, acts as a barrier between them and stomach acids and helps to heal them; 
5. inhibits activity of Helicobacter pylori bacteria; 
6. does not interfere with the production of prostaglandins essential to the mucosal lining of the stomach; 
7.strengthens these mucosal linings and stimulates production of protective mucous.


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