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Amantadine Hydrochloride

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Amantadine Hydrochloride, Amantadine HCL

CAS number: 665-66-7 

Molecular formula:C10H18ClN

Molecular weight: 187.71

Packing: 25kg/drum

Valid time: 3 years

Specification:

 

Test items

Specification

Results

Description

White or practically white, crystalline   powder, having a bitter taste

Conformed

Identification

The infrared spectrogram of the sample   corresponds to that of reference standard

Conformed

Clarity and color of solution

Clear and nearly colorless

Conformed

PH

3.0-5.5

3.8

Heavy metals

NMT 10ppm

Less than 10ppm

Related substances

Individual impurity: NMT 0.3%

0.08%

Total impurities: NMT 1.0%

0.1%

Assay

98.5%-101.5%

99.2%

Conclution

This product according to the Quantity   standard of Amantadine HCL USP40

 

Function

 

Amantadine hydrochloride Used as an antiviral drug. After entering the brain tissue, it can promote the release of dopamine, or delay the metabolism of dopamine and play an anti-tremor paralysis effect. It has obvious curative effect on paralysis and paralysis, relieves tremor, and has good rigidity. 48 hours after the onset of rapid drug use, the effect is obvious, and it has a good antipyretic effect in combination with antibiotics such as multiple inflammations, sepsis, and viral pneumonia.

 

 

Application

 

1) As Anti-virus medicine 

Used to make intermediate of anti-virus medicine for treating A2 type flu virus, has antipyretic effect in the clinical pharmacology;

Amend fremitus and anaesthesia of Parkinson's disease symptom.

2) As pharmaceutical intermediate

Amantadine Hcl can be used as intermeditate to  vildagliptin

3) As medicine to cure glaucoma

By blocking the NMDA receptor-mediated apoptosis, Amantadine Hcl has a great protective effect against RGC , then reduce and delay apoptosis of retinal tissue.

4) Raw material of catalyst

It can be as a raw material of catalyst to produce the new warm cataly, the applicant is very widely.

 


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